Pascal Lorentz
Dr. Michael Abanto
Director of the Nikon Center of Excellence
Head of the Microscopy Core Facility
Research Outline: Immunology and infectious diseases, neurosciences, cancer biology, and tissue development and regeneration.
Our Nikon Microscopy Ambassador Dr. Kevin Richein is a neuroscience researcher studying Alzheimer’s disease and the development of tools for neurodegenerative diseases. In this interview video, Dr. Richetin discusses how they chose the Nikon microscope because its software NIS-Elements allows seamless integration of analysis and automation. He emphasizes that this unique capability is incredibly valuable for tracking particles with extremely high resolution over extended periods, a feature that sets Nikon apart.
Kitasato University Kitasato Institute Hospital
Director, Department of Pathology
Dr. Ichiro Maeda
Currently there are various treatment methods under development that could provide optimal medical care in response to the pathological attributes of each patient. Therefore, the role required of pathological diagnosis, which is indispensable for the planning of treatment policies and strategies, is becoming more important than ever before. However, the shortage of trained pathologists who assume this role is a common issue, not only in Japan, but also worldwide. To solve this problem, digital pathology has been attracting attention. In this article, we asked Dr. Ichiro Maeda, Director of the Department of Pathology, Kitasato University Kitasato Institute Hospital, for his impressions of using the digital image display optical microscope "ECLIPSE Ui".
*Dr. Maeda has provided feedback to Nikon on this microscope’s features and clinical usefulness based on his own personal experience.
In April 2022, insurance coverage for infertility treatment started in Japan, making it easier for couples who want to conceive to receive ICSI treatment. However, in general, there is still a belief that “infertility is not a disease”, so there are many patients who suffer from anxiety or feel impatient during treatment. We interviewed Shoko Ieda and Sumi Shimamura of the Minatomirai Yume Clinic, who say that they find it rewarding to acknowledge these emotions and help such patients with the birth of their babies, about their impressions of using “ECLIPSE Ti2-I”.
*Customers have provided feedback to Nikon on this microscope’s features and clinical usefulness, based on their own personal experience
Matthew Kofron, Ph.D.
Professor, UC Department of Pediatrics
Alicia Ostmann
Cincinnati Cystic Fibrosis Theratyping Research Center
Kentaro Iwasawa, M.D.
Takebe Lab, Division of Gastroenterology
Research Outline: Child health improvement. Organoid creation. Drug efficacy for cystic fibrosis patients.
Professor Friedmann Kiefer, Ph.D.
Department of Intravital Molecular Imaging
Research Outline: Elucidation of how molecular mechanisms shape human cells and tissues biologically. Multiscale imaging.
Tetsuhisa Otani, Ph.D. Assistant Professor
Division of Cell Structure
Research Outline: Epithelial tissue.
Professor Won Do Heo, Ph.D.
Department of Biological Sciences
Research Outline: Optogenetic and bio-imaging technologies.
Dr. Hu Zhao, Principal Investigator
Research Outline: New tissue clearing methods, and building a neural connectome mapping platform based on these methods.
Takeshi Sasaki
Professor, Project Leader, M.D. Ph.D
The University of Tokyo Hospital
Dept. of Next-Generation Pathology Information Networking
In medicine, pathologists play an extremely important role in confirming observation. They are often making observations with a microscope for long periods of time and the physical and mental burden of this is heavy. Aiming to reduce such stress issues for pathologists, Nikon has developed a new microscope for pathological examination, the ECLIPSE Ui, which allows pathologists to view high-resolution images of specimens on a monitor, rather than looking through eyepieces. Here, Dr. Takeshi Sasaki of the University of Tokyo Hospital, who has evaluated this microscope, talks about his impressions of it.
*Dr. Sasaki has provided feedback to Nikon on this microscope’s features and clinical usefulness based on his own personal experience.
Director of the Department of Reproductive Medicine, Center for Regenerative Medicine, National Center for Child Health and Development
Hiroaki Miki, Professor
Yosuke Funato, Associate Professor
Osamu Hashizume, Assistant Professor
Division of Cellular and Molecular Biology, Department of Cellular Regulation
Research Outline: Analyzing the function of a membrane protein molecule called Cyclin M, which plays a role in ejecting magnesium ions from cells.
Beim Studium der Grundlagen der Naturwissenschaften spielt die Mikroskopie eine äußerst wichtige Rolle. Das Nikon ECLIPSE Ei wurde als Ausbildungsmikroskop mit dem Konzept entwickelt, ein “benutzerfreundliches Mikroskop zu sein, gerade für Studenten, die zum ersten Mal ein Mikroskop bedienen sollen“. Wir besuchten Frau Rika Izumi, Dozentin für Naturwissenschaften an der Rikkyo Niiza Junior and Senior High School, Saitama, Japan, wo das ECLIPSE Ei in den Kursräumen verfügbar ist. Von ihr wollten wir mehr erfahren über Hintergründe und Begründung für die Wahl dieses Mikroskops, die Erfahrungen der Benutzer sowie die Reaktionen der Studentinnen und Studenten.
Klinische Untersuchungen spielen eine wichtige Rolle in der medizinischen Versorgung. Ein klarer Fokus bei der Entwicklung des neuen Labormikroskops ECLIPSE Ci-L plus von Nikon lag auf dem Konzept, sowohl die physische als auch mentale Belastung von Klinikern und Labortechnikern, die täglich viel am Mikroskop arbeiten, zu reduzieren. In diesem Interview sprachen wir mit Dr. Akira Yoshikawa von der Abteilung für anatomische Pathologie des Kameda Medical Center – einem führenden Lehrkrankenhaus im südlichen Teil der Präfektur Chiba, Japan – über seine Gedanken nach dem Arbeiten mit diesem Mikroskop und den neuen Objektiven „CFI Plan Apochromat Lambda D“ im praktischen Alltagsgebrauch.
Associate Prof. Dr. Klazina Kooiman, Head of Therapeutic Ultrasound Contrast Agent Group, and Dr. Ines Beekers, Postdoctoral Researcher in the Department of Biomedical Engineering of the Thoraxcenter, Erasmus MC, Rotterdam, the Netherlands
Die Reproduktionsklinik Tokio, eine Kinderwunschklinik im dritten Stockwerk des Shiodome City Center, einem hochmodernen Bürogebäude im Shiodome-Viertel im Zentrum von Tokio, hat viele Patienten, die auch an Wochentagend abends auf eine Behandlung warten. Wir sprachen mit Shimpei Mizuta und Tomohiro Maekawa, die das Inverse Mikroskop Ti2 für die Spermiensortierung und die intrazytoplasmatische Spermieninjektion (ICSI) verwenden, über ihre Gedanken zu ihrer Arbeit und ihre Eindrücke vom Ti2.
Dr. Yohei Yamauchi, Principal Investigator, Cell biologist of viral infections, School of Cellular and Molecular Medicine, University of Bristol, UK
Virology and Microbiology
Baylor College of Medicine
Houston, Texas, USA
Therapeutic Ultrasound Contrast Agent Group, Thoraxcenter, Department of Biomedical Engineering, Erasmus MC, Rotterdam
Director: MRC Human Genetics Unit, University of Edinburgh
Dr. Steven Nedellec, Facility Manager of MicroPICell, Université de Nantes, France and Dr. Tiphaine Douanne, Universite de Nantes, Signaling in Oncogenesis, Angiogenesis and Permeability, CRCINA INSERM U1232, France
Senior Lecturer in Cardiovascular Science, University of Birmingham
Division of Bio-Imaging, Proteo-Science Center (PROS), Ehime University
Division of Analytical Bio-Medicine, Advanced Research Support Center (ADRES), Ehime University
Graduate School of Medicine, Ehime University
The advanced Fluorescence Imaging and Biophysics Group, ICFO-Institute of Photonic Sciences
Professor and Vice Chairman of the Dept. of Cell Biology
Director and Founder of the Center for Biologic Imaging
University of Pittsburgh
Pittsburgh, Pennsylvania, USA
Professor and Vice-Chairman of the Department of Cellular and Molecular Pharmacology
Investigator, Howard Hughes Medical Institute (HHMI)
The University of California, San Francisco San Francisco, CA, USA
Research Institute for Electronic Science
Sapporo, Hokkaido, Japan
Institute of Experimental Medicine of the Hungarian Academy of Sciences (IEM HAS)
Budapest, Hungary
Group Leader (Royal Society University Research Fellow)
Randall Division of Cell and Molecular Biophysics
King’s College London
London, United Kingdom
Professor of Applied Physics, Department of Physics, University of Genoa
Director of the Department of Nanophysics, Istituto Italiano di Tecnologia
Professor, Department of Physics, University of Illinois at Urbana-Champaign
Assistant Professor, Department of Pharmaceutical Chemistry, Department of Biochemistry and Biophysics, University of California, San Francisco
Senior Team Leader, Laboratory for Cell Function Dynamics, RIKEN Brain Science Institute
Department of Cell Science, Institute of Biomedical Science, Fukushima Medical University
The Imagerie-Gif light microscopy core facility is a member of the France Bioimaging Infrastructure. The facility is hosted by the Institute for Integrative Biology of the Cell (I2BC) at Gif sur Yvette, France.
Staffan Strömblad Ph.D. is group leader at the prestigious Karolinska Institutet, Stockholm, Sweden, an institution that awards the Physiology Nobel Prize yearly. He is also the head of the Live Cell Imaging Facility (LCI), in which the Nikon Center of Excellence for live cell imaging is integrate.
The Faculty of Life Science (SV) at the École Polytechnique Fédéral de Laussane (EPFL), Switzerland, has a long record of excellence in research applied to life sciences
Chief Scientific Officer at Natural Bio-Medicine SpA,
Aboca Group
So-called iPS cells are attracting considerable interest as pluripotent stem cells that may open up a whole new world of medicine. The Center for iPS Cell Research and Application (CiRA) at Kyoto University is pursuing a wide range of research activities that aim to realize regenerative medicine utilizing iPS cells. The Nikon BioStation CT cell culture observation system is being used in this iPS cell research and is contributing to its efficiency.
We were pleased to have had an opportunity to speak with Masato Nakagawa, who is engaged in iPS cell research at CiRA.
Full time professor at the Laboratory of Experimental Epileptology and Cognition Research hosted in the Life & Brain Center, Part of the University of Bonn.
Note: The institutions and job titles listed with each researcher reflect their affiliation at the time of the interview.
