Nikon Instruments Inc. | Americas
Artboard 1
en Change Region

Global Site

Upright Microscope

Advanced research and clinical upright microscope combining superb optics with optional motorized accessories for system expandability and flexibility

With its robust performance, bright and sharp optical system, flexible stratum structure and motorized options, the ECLIPSE Ni-U is the standard model in Nikon's advanced upright microscope series. It can support a wide range of observations, from clinical examinations to bioscience research.

Download ECLIPSE Ni/Ci Brochure (8.54MB)

Ni-U configured with an ergonomic binocular tube

Key Features

Stratum structure for system expansion

Nikon's proprietary stratum structure enables simultaneous mounting of two optical paths on one microscope to support various applications.

This structure allows double layer mounting of an epi-fluorescence illuminator, a photoactivation unit and a back port unit, developed for the first time for upright microscopes to enable simultaneous photoactivation and imaging, and simultaneous multichannel imaging.

High-speed motorized accessories

Motorized options for the objective nosepiece, epi-fluorescence cube turret and shutter are available.

Supreme optical performance

Nano Crystal Coat technology

Employed for the first time in microscope objectives, this anti-reflective coating consists of nanometer-size particles. It is based on semiconductor manufacturing technology and is also used for Nikon camera lenses. The coating's coarse structure and uniform arrangement of particles in a spongy construction result in extremely low reflective indices.

without nano crystal coat

with nano crystal coat

CFI Plan Apochromat Lambda D series

The high-refractive index glass used in the oil-immersion objectives provides uniform brightness and high image quality up to the periphery of a large 25mm diagonal field of view, enabling efficient acquisition of seamless stitched images and supports macro imaging of large samples. High transmittance and chromatic aberration correction over a wide wavelength range from 405 nm to 850 nm enable reliable quantitative data acquisition for intensity analysis of nuclear staining. These high NA lenses are ideal for brightfield and DIC observations, as well as fluorescence and confocal observations.

Water dipping objective lenses

With a long working distance and high NA, these objectives provide excellent transmission in near IR wavelength range. The axial chromatic aberration of CFI Apochromat NIR 40X/60X W has been corrected up to 850 nm, providing high-resolution images of minute structures in thick specimens during IR-DIC observation. The CFI75 Apochromat 25XC W series and CFI Plan 100XC W also feature high NA andlong working distances. With chromatic aberration corrected in the IR region, these objectives are ideal for multiphoton excitation observation. In addition, these lenses provide correction collars to compensate for temperature- and depth-induced spherical aberration, resulting in crystal clear images of areas deep within thick specimens.

Uniformly bright illumination

A built-in "fly-eye" lens ensures uniform and bright illumination of the field of view, from edge-to-edge, at any magnification.

Fluorescence noise elimination

Nikon’s proprietary noise terminator mechanism is employed in the epi-fluorescence cube turret and filter cubes. The S/N ratio has been dramatically improved by thoroughly eliminating stray light in the filter cubes, allowing images of weak fluorescent signals to be captured with high contrast and brightness.

Ultimate ease of operation

Simple digital imaging

Images can be captured with Digital Sight cameras by simply pressing the image capture button located on the microscope base.

Image capture button

Absolute comfort

The ergonomic tube and stage handle height adjustment mechanisms allow comfortable viewing positions. The space-saving microscope base enables users to maximize their work area. A simple remote control pad for easy operation of motorized accessories is also available.

Simple remote control pad