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Upright Clinical Microscopes

Clinical and laboratory microscopes featuring LED illumination*, providing stress-free operation for routine use

To meet the demands of clinical laboratory specialists and researchers, Nikon has reviewed all aspects of microscope usability to develop the ECLIPSE Ci series of microscopes, which combines superior functionality with operational ease. The Ci is designed to ensure natural posture while viewing images, sample changing and capturing images. Bright, eco-friendly LED illumination reduces the need for frequent lamp replacement*. A variety of accessories are available that support various imaging techniques.

* Halogen model (Ci-S) is also available

This product is available for clinical use in the United States. Please contact your local Nikon dealer for information on clinical use of this product in your country.

Download ECLIPSE Ci-L plus Brochure (7.75MB)

Motorized model with LED illumination

Equipped with motorized nosepiece and automatic intensity recall, the Ci-E is ideal for applications that require frequent magnification switching.

Manual model with LED illumination

Equipped with LCD and Light Intensity Management (LIM) function based on ECLIPSE Ci-L which is designed with a focus on ease-of-use as well as the health and working styles of people involved in research.

Manual model with halogen illumination

Suitable for applications requiring a traditional halogen light source.

Key Features

Motorized magnification switching

  • Ci-E

Magnification can be easily changed during observation with the touch of a button on the ECLIPSE Ci-E microscope body. The buttons can also be programmed for specific objective lenses for easy switching between specific pairs. User-defined light intensity for each magnification is automatically saved and reproduced when magnification is changed. The remote control pad can also be used to easily change magnifications.

Nosepiece rotation buttons

Remote control pad

Bright and uniform Eco-illumination

  • Ci-E
  • Ci-L plus

The Eco-illumination* is a low-power-consuming, eco-friendly illumination system that produces uniform brightness and reduces the cost and effort of lamp replacement, thanks to its 60,000 hour, high-luminescent LED. By combining a collimator lens, fly-eye optics and LED illumination, bright and edge-to-edge uniform images can be obtained even at high magnifications. The LED illuminator features low-heat generation and provides the same color temperature at every magnification.

* Halogen model (Ci-S) is also available

Enhanced operational ease

  • Ci-E
  • Ci-L plus
  • Ci-S

Observation with a natural posture

Using the ergonomic binocular tube, which features an eyepiece that can be inclined from 10° to 30°and extended up to 40 mm, the microscope can be adjusted for natural posture. The eyelevel riser lifts the eyepiece tube in 25 mm increments (up to 100 mm*) and can easily be adapted to suit users with different eye-point heights.

* Up to 50 mm with ergonomic binocular tube.

Ergonomic binocular tube

Eyelevel riser

User-friendly stage operation

With the addition of a nosepiece spacer, the stage height can be lowered 20 mm from the standard position, reducing strain during frequent specimen change. The stage handle height can also be changed to ensure a comfortable hand position. The stage height can be locked using the refocusing knob, allowing quick refocusing after specimen changes. The stage is coated with a high-durability, scratch-resistant ceramic coating.

Without spacer (left), with spacer (right)

Height adjustable stage handle

Ceramic-coated stage

Easy on the eyes, even during extended use

  • Ci-L plus

Maintains optimal brightness

The light intensity management (LIM) function developed by Nikon automatically stores any changes to brightness settings. This helps avoid drastic changes in brightness when switching between different magnifications during observation, thereby helping to mitigate eye strain.

Low-magnification objective lensHigh-magnification objective lens

with LIM

Low-magnification objective lensHigh-magnification objective lens

without LIM

Keep the same observation posture with automatic brightness adjustment

The LIM function saves and recalls the optimal brightness level for each objective, eliminating the need to manually adjust the illuminator and change posture every time you switch objective lenses.

Effortless image capturing

  • Ci-E
  • Ci-L plus
  • Ci-S

One simple click of the image capture button on the microscope base during observation enables the Digital Sight camera to capture the specimen image. Camera control software for tablet PC NIS-Elements L is equipped with a scene mode that can automatically set the optimum shooting conditions for each observation method. Since it has a network function, you can share images with a remote PC.

* NIS-Elements L is not for clinical diagnostic use.

Image capture button

NIS-Elements L camera control software for tablet PC

Digital pathology via network

Enjoy enhanced efficiency during observations

  • Ci-L plus

❶ ECO mode: ON
❷ LIM function: ON
❸ Objective name
❹ Magnification
❺ Brightness state

Status Display for easy confirmation at a glance

Quickly and easily check magnification and brightness settings using the display at the base of the microscope without changing your observation posture.

Turning the nosepiece automatically adjusts the scale bar

The scale bar on the PC display changes automatically to match the magnification level, eliminating the need to set the scale manually.

*Sold separately: Software (NIS-Elements D / BR / AR), Nikon recommended camera required

Versatile observation techniques

  • Ci-E
  • Ci-L plus
  • Ci-S

Phase contrast

High-contrast images with neutral background coloration regardless of the magnification range can be captured. This observation technique is suitable for observation of unstained structures.

Phase contrast accessories and objective lenses

Simple polarizing

Ideal for observing bi-refringent samples such as collagen, amyloids and crystals.

* Two types of analyzer are available: intermediate tube type and nosepiece slider type.

2.8-Dihydroxyadenine crystals, Simple polarizing, CFI Plan Fluor 40X
Department of Clinical laboratory, Nihon University Itabashi Hospital

Simple polarizing accessories

Sensitive color polarizing

Enables Identification of uric acid crystals by changes in the interference color. This technique is ideal for gout and pseudo-gout tests.

* Two types of analyzer are available: intermediate tube type and nosepiece slider type.

Sodium urate crystals, Sensitive color polarizing, CFI Plan Fluor 40X
Department of Clinical laboratory, Nihon University Itabashi Hospital

Sensitive color polarizing accessories


Enables clear observation of blood or minute structures such as flagella. Dry- and oil-type condensers are available. An expander lens is utilized for brighter imaging.


Compact epi-fluorescence attachments that utilize noise terminating mechanisms allow weakly fluorescing specimens to be captured with great clarity and brightness. Both CI-FL epi-fluorescence attachment (incorporates up to 4 filter cubes) and D-FL epi-fluorescence attachment (incorporates up to 6 filter cubes) allow easy switching of filter cubes. High-optical-performance objective lenses for epi-fluorescence imaging, including the CFI Plan Apochromat Lambda series and the CFI Plan Fluor series, are available.

CI-FL epi-fluorescence attachment and filter cubes

ECLIPSE Ci Remote controlled model

  • Ci-E

The ECLIPSE Ci-E robotic model allows users to view live images from a remote site and have full control of the microscope with virtually any tablet or smartphone.

  • Remotely select a full array of objectives (from 1x-100x)
  • While viewing live images, stitch multiple fields of view into a large single high magnification image.
  • No waiting on slides to be scanned and uploaded.
  • No large data storage costs.


  • Ci-E
  • Ci-L plus
  • Ci-S

Objective lenses to meet diverse needs

We offer a wide range of objective lenses that are optimal for laboratory and observation work such as the Plan Fluor 10X with its long working distance of 16 mm, and the CFI Plan Apochromat Lambda Series featuring the excellent quality in optical performance.

Microscope Digital Camera DS-Fi3

A 5.9 megapixel CMOS image sensor allows for the capture of images up to 2880 x 2048 pixels with color tones that faithfully represent the specimen.

NIS-Elements L Imaging Software

By connecting the Digital Sight 1000 or DS-Fi3 to a tablet PC with NIS-Elements L installed, images of specimens under observation can be shared with other PCs via a network. The software also contains a variety of measurement and annotation functions.