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Microscope System for ICSI

Superior optical performance and precision for ICSI

Nikon microscopes have played a significant role from the early days of Intracytoplasmic Sperm Injection (ICSI) and continue to contribute to the advancement of this field through superior optical performance and precision.

The ECLIPSE Ti2-U IVF provides an ultra-stable platform for performing precision manipulation procedures such as ICSI. The intermediate magnification switching function (1.5X) allows easy switching of observation magnifications without changing objectives.

Product is available in the US, Europe, and Japan only

The ECLIPSE Ti2-U IVF is an MDR certified product in Europe.

Download ECLIPSE Ti2-U IVF Brochure (1.62MB)

Key Features

Nikon Advanced Modulation Contrast (NAMC) observation

The Nikon Advanced Modulation Contrast (NAMC) technique enables high-contrast observation of colorless and transparent samples through plasticware. NAMC produces a pseudo-relief shading effect, ideal for ICSI. The direction of shading can be adjusted through 360 degrees by turning the modulator in an NAMC objective. CFI S Plan Fluor ELWD NAMC objectives are equipped with a modulator ring clamping mechanism to prevent accidental rotation of the modulator ring while rotating the correction collar.

A sperm cell can be clearly observed in the injection pipette.

Images courtesy of: Derek Keating, B.A. and Gianpiero D. Palermo, MD, PhD., Andrology and Assisted Fertilization: Weill Cornell Medicine - Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine.

CFI S Plan Fluor ELWD NAMC 20XC (left)
CFI S Plan Fluor ELWD NAMC 40XC (right)

CFI Achromat NAMC 10XF (left)
CFI Achromat LWD NAMC 20XF (middle)
CFI Achromat LWD NAMC 40XC (right)

Spindle observation

This polarized light technique enables finely detailed observation of spindle bodies for oocyte assessment and the elimination of spindle damage during sperm injection.

Switching between spindle observation and NAMC is fast and easy.

The following objectives are compatible with spindle observation: CFI S Plan Fluor ELWD NAMC 20XC and CFI S Plan Fluor ELWD NAMC 40XC.

TI2-C-SO Spindle observation system