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Smart Imaging System

Research Microscope Power in a Benchtop Assay Instrument

Simple Operation

Minimal experimental setup and complexity by AI-driven assays and analysis.

Easy Cellular Imaging

No need to master complicated microscope hardware and software – ECLIPSE Ji makes data collection and cellular imaging assays easy.

High Quality Optics

Renowned Nikon optics provide clear and sharp images on plate assay devices.

Download ECLIPSE Ji (for Assays) (4MB)

Key Features

Smart Experiments with Automated Assays

Utilizing Nikon’s precision optical hardware, all of the advantages of high sensitivity and resolution from a research-level microscope are retained by an AI-driven, easy-to-operate benchtop laboratory instrument.

Preconfigured and optimized turnkey assay experiments minimize time spent defining parameters, maximizing data collection.

Standard Assays

Intensity Measurement

Compares protein expression level changes in cells and cell nuclei in multiple wells.

Application Note

Cell Counting (endpoint)

Counts the number of cell nuclei in a fixed sample and the area of the well occupied by cells.

Application Note

Transfection Efficiency

Investigates the percentage of cells expressing the target protein, and reports the expression efficiency.

Application Note

Size & Morphological analysis

Analyzes cellular morphology with measurements of the cell nucleus, cytoplasm, and the size of the cell region.

Application Note


Measures the percentage of dead cells among all cells and evaluates cytotoxicity.

Application Note

Optional Assays


Measures the percentage of apoptotic cells among the population.

Application Note

DNA damage (gamma H2AX)

Analyzes DNA damage foci within individual cell nuclei.

Application Note

Nuclear Translocation

Measures the nuclear translocation of NF-κB, indicating an extra-cellular stimulus.

Application Note


Measures the number of autophagosomes, their area, and their fluorescence intensity.

Application Note


Measures the number, area, and fluorescence intensity of bioparticles taken into the cell by phagocytosis.

Application Note


Measures the number, area, and fluorescence intensity of granules formed by endocytosis, which are taken up from outside the cell.

Application Note

Micronucleus test

Measures the number of cells containing micronuclei or multiple nuclei.

Application Note

Mitochondrial toxicity

Measures the number, area, and fluorescence intensity of mitochondria.

Application Note

Effortless Results using AI

ECLIPSE Ji’s Smart Experiment software interface uses newly developed artificial intelligence (AI), implemented to minimize errors and maximize data collection.


Load a plate

Select assay / Input basic information

Check the shooting results and analysis results

step 1step 2step 3step 4


AI automatically judges plate status and automatically adjusts acquisition conditions

Actual Acquisition/analysis/data display

Automatic acquisition, data extraction, graphing under optimized acquisition conditions


One click export of the data

Single-Cell Imaging and Analysis with Ease

AI based on Deep Learning defines acquisition settings and image analysis parameters, saving researchers valuable time at the microscope.

Automatic Plate Detection

Plate type and dimensions are automatically detected. There is no need to select from lists or manually enter plate data.

Automatic detection of samples

A rapid preview across the entire plate determines which wells have sample present, allowing users to easily skip empty wells.

Automatic calculation of optimal exposure settings

There is no need for troublesome tuning of light intensity and exposure time. The optimal exposure settings for image analysis are automatically calculated from the luminance values of all wells.

Automatic alignment of the plate

No alignment work is required. The system automatically detects and corrects the plate position.

User Interface Designed for Data-Rich Microscopy

Images and corresponding analysis data for the plate, well, and each cell is contained in an interactive and linked interface. Users can navigate and quickly visualize trends and results.