CrestOptics CICERO

Adaptable confocal imaging for today’s research

CICERO is a versatile and compact spinning-disk confocal unit, offering a complete fluorescence imaging solution that makes advanced imaging accessible to all laboratories, supporting a wide range of applications. Achieve clear, high-speed fluorescence imaging across experiments, from rapid live-cell studies to detailed 3D reconstructions. Minimize crosstalk in multicolor acquisition and rely on precise excitation and detection powered by multiple laser lines and high-sensitivity cameras. With its robust design and intuitive interface, CICERO delivers dependable performance for a wide range of research applications.

Key Features

Compact

Designed as a plug-and-play system, CICERO integrates widefield and spinning-disk imaging in a single streamlined unit. Its small footprint allows it to fit easily into crowded lab spaces without sacrificing performance, making it ideal for facilities where bench space is at a premium.

By combining cost efficiency with advanced imaging capabilities, CICERO ensures that confocal microscopy is accessible to laboratories of all sizes, from core facilities to individual research groups.

Versatile

Engineered for seamless integration, CICERO can be mounted on both inverted and upright microscopes, adapting to diverse laboratory setups. It is fully compatible with a broad array of detectors, illumination sources, and peripheral devices, providing flexibility for specialized workflows. This adaptability allows researchers to tailor the system to their experimental needs, ensuring that CICERO supports applications ranging from basic fluorescence studies to advanced, multi-modal imaging approaches.

Compatible with Nikon inverted and upright microscopes, CICERO integrates seamlessly with detectors, illumination sources, and peripherals to support diverse workflows.

Fast

CICERO delivers rapid, high-sensitivity imaging with acquisition speeds reaching up to 15K frames per second. This performance makes it ideally suited for capturing fast biological processes without sacrificing image quality. A large field of view, up to 22 mm, enables researchers to collect more data in a single experiment, improving throughput and efficiency. Together, these features empower scientists to study dynamic samples with both speed and precision.

Capture rapid biological processes with acquisition speeds up to 15K fps and a large 22 mm field of view for greater throughput.

Powerful

With support for up to five imaging channels, including near-infrared detection, CICERO provides flexibility for complex, multicolor experiments. Flat, uniform illumination ensures consistent signal intensity across the entire field, enhancing data quality and enabling more effective image stitching. These capabilities make CICERO a robust tool for generating comprehensive datasets, supporting experiments that demand both spectral breadth and spatial accuracy.

With up to five channels extending into the NIR and flat, uniform illumination, CICERO delivers high-quality, multicolor data across large sample areas.

Easy-to-Operate

Designed with the researcher in mind, CICERO allows rapid switching between widefield and confocal imaging modes. This smooth transition streamlines experimental workflows and enables effortless 3D sectioning at the flip of a switch. By reducing setup complexity and saving time, CICERO makes advanced confocal imaging more approachable, ensuring that users can focus on their science rather than the instrumentation.

Switch effortlessly between widefield and confocal imaging to streamline workflows and achieve true 3D sectioning in seconds.

Flexible

At the heart of CICERO is a universal illuminator with multiple excitation options, giving researchers the freedom to select the configuration that best matches their needs. Whether equipped with a 5-color laser system or a 4-color LED module, the system provides the adaptability required for a wide range of applications. This flexibility ensures that CICERO can evolve alongside changing research demands, making it a sustainable long-term solution for fluorescence imaging.