Research Microscope Power in a Benchtop Assay Instrument
Minimal experimental setup and complexity by AI-driven assays and analysis.
Easy Cellular Imaging
No need to master complicated microscope hardware and software – ECLIPSE Ji makes data collection and cellular imaging assays easy.
High Quality Optics
Renowned Nikon optics provide clear and sharp images on plate assay devices.
Utilizing Nikon’s precision optical hardware, all of the advantages of high sensitivity and resolution from a research-level microscope are retained by an AI-driven, easy-to-operate benchtop laboratory instrument.
Preconfigured and optimized turnkey assay experiments minimize time spent defining parameters, maximizing data collection.
Compares protein expression level changes in cells and cell nuclei in multiple wells.
Cell Counting (endpoint)
Counts the number of cell nuclei in a fixed sample and the area of the well occupied by cells.
Investigates the percentage of cells expressing the target protein, and reports the expression efficiency.
Size & Morphological analysis
Analyzes cellular morphology with measurements of the cell nucleus, cytoplasm, and the size of the cell region.
Measures the percentage of dead cells among all cells and evaluates cytotoxicity.
Measures the percentage of apoptotic cells among the population.
DNA damage (gamma H2AX)
Analyzes DNA damage foci within individual cell nuclei.
Measures the nuclear translocation of NF-κB, indicating an extra-cellular stimulus.
Measures the number of autophagosomes, their area, and their fluorescence intensity.
ECLIPSE Ji’s Smart Experiment software interface uses newly developed artificial intelligence (AI), implemented to minimize errors and maximize data collection.
Load a plate
Select assay / Input basic information
Check the shooting results and analysis results
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AI automatically judges plate status and automatically adjusts acquisition conditions
Actual Acquisition/analysis/data display
Automatic acquisition, data extraction, graphing under optimized acquisition conditions
One click export of the data
AI based on Deep Learning defines acquisition settings and image analysis parameters, saving researchers valuable time at the microscope.
Automatic Plate Detection
Plate type and dimensions are automatically detected. There is no need to select from lists or manually enter plate data.
Automatic detection of samples
A rapid preview across the entire plate determines which wells have sample present, allowing users to easily skip empty wells.
Automatic calculation of optimal exposure settings
There is no need for troublesome tuning of light intensity and exposure time. The optimal exposure settings for image analysis are automatically calculated from the luminance values of all wells.
Automatic alignment of the plate
No alignment work is required. The system automatically detects and corrects the plate position.
Images and corresponding analysis data for the plate, well, and each cell is contained in an interactive and linked interface. Users can navigate and quickly visualize trends and results.
Outside of plate assays, ECLIPSE Ji can also serve as a digital research microscope, and can be integrated with a variety of peripheral hardware ranging from filter wheels through confocal systems such as "AX", or high-sensitivity cameras.
*The design and specifications may differ from the actual product.