Research Microscope Power in a Benchtop Assay Instrument
Simple Operation
Minimal experimental setup and complexity by AI-driven assays and analysis.
Easy Cellular Imaging
No need to master complicated microscope hardware and software – ECLIPSE Ji makes data collection and cellular imaging assays easy.
High Quality Optics
Renowned Nikon optics provide clear and sharp images on plate assay devices.
Hauptmerkmale
Smart Experiments with Automated Assays
Utilizing Nikon’s precision optical hardware, all of the advantages of high sensitivity and resolution from a research-level microscope are retained by an AI-driven, easy-to-operate benchtop laboratory instrument.
Preconfigured and optimized turnkey assay experiments minimize time spent defining parameters, maximizing data collection.
Standard Assays
Intensity Measurement
Compares protein expression level changes in cells and cell nuclei in multiple wells.
Cell Counting (endpoint)
Counts the number of cell nuclei in a fixed sample and the area of the well occupied by cells.
Transfection Efficiency
Investigates the percentage of cells expressing the target protein, and reports the expression efficiency.
Size & Morphological analysis
Analyzes cellular morphology with measurements of the cell nucleus, cytoplasm, and the size of the cell region.
Cytotoxicity
Measures the percentage of dead cells among all cells and evaluates cytotoxicity.
Optional Assays
Apoptosis
Measures the percentage of apoptotic cells among the population.
DNA damage (gamma H2AX)
Analyzes DNA damage foci within individual cell nuclei.
Nuclear Translocation
Measures the nuclear translocation of NF-κB, indicating an extra-cellular stimulus.
Autophagy
Measures the number of autophagosomes, their area, and their fluorescence intensity.
Effortless Results using AI
ECLIPSE Ji’s Smart Experiment software interface uses newly developed artificial intelligence (AI), implemented to minimize errors and maximize data collection.
| Input | Output | ||
|---|---|---|---|
Load a plate | 
Select assay / Input basic information | 
Check the shooting results and analysis results | 
Report |
| step 1 | step 2 | step 3 | step 4 |
| ECLIPSE Ji | Pre-AcquisitionAI automatically judges plate status and automatically adjusts acquisition conditions |
Actual Acquisition/analysis/data displayAutomatic acquisition, data extraction, graphing under optimized acquisition conditions |
ReportingOne click export of the data |
Single-Cell Imaging and Analysis with ease
AI based on Deep Learning defines acquisition settings and image analysis parameters, saving researchers valuable time at the microscope.
Automatic Plate Detection
Plate type and dimensions are automatically detected. There is no need to select from lists or manually enter plate data.
Automatic detection of samples
A rapid preview across the entire plate determines which wells have sample present, allowing users to easily skip empty wells.
Automatic calculation of optimal exposure settings
There is no need for troublesome tuning of light intensity and exposure time. The optimal exposure settings for image analysis are automatically calculated from the luminance values of all wells.
Automatic alignment of the plate
No alignment work is required. The system automatically detects and corrects the plate position.
Produktbroschüre
Digitalmikroskopie
- ECLIPSE Ji
- ECLIPSE Ui