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Center of Excellence
The Baylor College of Medicine Nikon Center of Excellence housed in the Center for Precision Environmental Health (CPEH) provides state-of-the-art technology to support cutting edge research converging on epigenetics, cancer biology, birth defects and environmental factors that ultimately shape disease susceptibility and outcome. The Nikon platforms will be used to leverage imaging in a variety of model systems including cell culture models, zebrafish, C. elegans and mouse/human tissues and sections.
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The AX R is a recently developed iteration of Nikon’s flagship confocal system, and is capable of 2k resonant scanning in an expanded 25 mm FOV for fast, gentle imaging of sensitive samples.
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
AX R resonant scanning confocal microscope system
D-LEDI LED Fluorescence for DAPI/GFP/DsRED/Cy5
NIS-Elements High Content software with 2D/3D deconvolution and extended depth of focus
Utilizing Structured Illumination Microscopy (SIM), this system exceeds the diffraction limit of traditional imaging systems, and is ideal for resolving structures ~100 nm in size. (XY resolution 100-115 nm, Z resolution 270 nm)
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
This widefield system is capable of large sample imaging experiments, and uses Nikon’s flagship ECLIPSE Ti2 inverted microscope base. It is also equipped with NIS-Elements 2D/3D Deconvolution and Clarify.ai for enhanced image quality.
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
This system allows for fast, gentle image acquisition, and is ideal for brightfield slide scanning in live and fixed cells.
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
Yokogawa CSU-W1 spinning disk confocal
This inverted ECLIPSE Ti2 microscope is equipped for super-resolution imaging applications, including N-STORM, TIRF and FRAP imaging. It is best suited for single molecule imaging in live and fixed cells.
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
System capable of fast, large field of view imaging in fluorescence, brightfield, plate and slide scanning experiments. Suitable for live and fixed cells.
ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
Stereo microscope with 25X zoom range, suitable for fluorescence imaging, developmental studies, live and fixed cells.
SMZ25 motorized stereo microscope