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King’s College London


Center of Excellence

King’s College London

The King’s College London Nikon Centre of Excellence is a light microscopy core facility situated within the Maurice Wohl Clinical Neuroscience Institute. The aim of the Centre is to support researchers with advancing their understanding of the molecular, cellular and functional basis of neurological and psychiatric disorders and the discovery, implementation and evaluation of novel diagnostic tools and therapeutic interventions.


Academic Director

Deepak P. Srivastava, Ph.D.

Facility Manager

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King's College London
Denmark Hill
United Kingdom

Systems Available

AX R Confocal with ECLIPSE Ti2-E Inverted Microscope

Nikon's AX R confocal features a 25 mm FOV, up to 8192 x 8192 pixel resolution, and is equipped with AI-based tools for simplifying acquisition and analysis. The AX R includes our high definition resonant scanner, which features a next-generation optical non-linear sampling digitizer, supporting imaging at high pixel densities of up to 2048 x 2048, and with superior image quality compared to other currently available resonant scanning systems.

A1R HD Confocal with ECLIPSE Ti-E Inverted Microscope

Capturing high-quality confocal images at ultrahigh-speed and enhanced sensitivity with a resonant scanner and galvano scanner, Nikon's A1R HD is a powerful tool for the imaging and visualization of intracellular dynamics and interaction.

CSU-X1 Spinning Disk Confocal with ECLIPSE Ti-E Inverted Microscope

The Yokogawa CSU-X1 spinning disk confocal combined with Nikon’s ECLIPSE Ti-E inverted research microscope platform provides fast, high-resolution 4D imaging of living cells with minimal effects of photo-damage. The Ti-E microscope is equipped with Perfect Focus (PFS) to enable long time-lapse imaging without focus drift. The system is also equipped with a fast, laser-based raster-scanning device (Miniscanner) for photobleaching and photostimulation.

A1R Multiphoton with ECLIPSE Ni-E FN Upright Microscope

Nikon's A1R HD multiphoton microscope enables high speed, deep tissue imaging in live organisms with unprecedented sensitivity and clarity. The system features an ultra-high speed resonant scanner capable of 420 fps imaging, a galvanometric scanner for high-resolution imaging, high-sensitivity GaAsP Multi Detector in both episcopic and diascopic imaging paths to optimize signal detection and high N.A. objective lenses designed for high-resolution, deep tissue imaging.

ECLIPSE Ti-E PFS Inverted Microscope System

The ECLIPSE Ti-E with Perfect Focus is Nikon's market leading inverted microscope system offering improved system speed, increased flexibility and efficient multi-mode microscopy as part of a fully-integrated microscope system that is ideal for high-end research and live cell imaging. Perfect Focus is Nikon's exclusive focus correction system that combats axial focus fluctuations in real time during long-term imaging investigations.

N-STORM with ECLIPSE Ti2-E, TIRF, and Dual Camera

N-STORM is a super-resolution microscope system that combines “STochastic Optical Reconstruction Microscopy” technology and Nikon's ECLIPSE Ti2-E research inverted microscope. The N-STORM super-resolution microscope provides dramatically enhanced resolution that is 10 times that of conventional optical microscopes.