Application Notes

Cytotoxicity assay using AI-driven, fully automated ECLIPSE Ji

September 2023

ECLIPSE Ji with Smart Experiment software enables seamless experiments from image acquisition to analysis and graph creation. Pre-trained Artificial Intelligence (AI) and pre-defined imaging processes automatically optimize image acquisition and analysis settings, providing visualized data and EC50 information with simple operation. Cytotoxicity analysis is a versatile assay used in a variety of biological research, such as studying the effects of pharmacological compounds, development of culture media and scaffolds for cell culture, or elucidation of cellular physiology. This application note introduces an example of using the Cytotoxicity module of Smart Experiment to visualize the dose-dependent induction of cell death due to staurosporine and quantify the effect of the drug by calculating the EC50.