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KU Leuven



KU Leuven

The VIB Bio Imaging Core at the VIB – KU Leuven Center for Brain has the goal to support imaging from in vitro to in vivo, from millimeter to Ångström, from morphology to mechanism and from image to information. The mission is to facilitate and lower as much as possible the threshold for scientists to get access to know-how for microscopy experiments and measurement time on state-of-the-art devices. The core enables the scientific questions in the center and beyond, by providing researchers with input for experimental design, image acquisition, and novel image analysis schemes. A general aim is to innovate and lead by state-of-the-art imaging.

The core has a broad portfolio and supports many applications from super-resolution to the mesoscale. The core runs 10+ high-end devices and takes pride in its support for image analysis (infrastructure and expertise). The core’s research focuses on the development of new imaging technology and analysis that is connected to the neurodegenerative focus of the center.

Overall, neurons, neuronal tissue as well as whole organs from a multitude of model systems are the daily imaging business in this core, and the experts in this unit are employing a vast number of different applications for empowering the research of its users.

Reach out to us; we are happy to engage with your science.


Head of VIB BioImaging Core Leuven

Pablo Hernandez Varas

Facility manager VIB BioImaging Core Leuven

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VIB BioImaging Core Leuven
Herestraat 49, box 602
3000 Leuven


KU Leuven

Systems Available

AX Confocal Microscope System

Nikon's AX confocal features a 25 mm FOV, up to 8192 x 8192 pixel resolution, and is equipped with AI-based tools for simplifying acquisition and analysis.

ECLIPSE Ti2-E Inverted Microscope with N-SIM S Super-Resolution

The ECLIPSE Ti2-EN-SIM S super-resolution microscope is a unique high-speed structured illumination system that achieves acquisition speeds of up to 15 fps, enabling fast biological processes to be captured at twice the spatial resolution of conventional light microscopes (up to 115nm in XY). 

ECLIPSE Ti-E Inverted Microscope with A1R HD25 Confocal

Confocal point scanning microscope equipped with a spectral detector, an Okolab incubator for environmental control (T + CO2) and a TIRF unit

ECLIPSE Ni-E Upright Microscope with A1R HD25 Confocal

Nikon's ECLIPSE Ni-E / A1R HD25 is a fast and gentle microscope system well suited to applications in stem cell biology and regenerative medicine.

ECLIPSE Ni-E Upright Microscope with Marzhauser Slide Express 2

The Nikon ECLIPSE Ni-E + Marzhauser Slide Express 2 + Hamamatsu Orca Flash 4.0 and Nikon DS-Fi3 is an upright widefield microscope system configured for high content imaging of slides.

ECLIPSE Ti-E Inverted Microscope with C2+ Confocal

The C2+ confocal microscope provides powerful and robust imaging capabilities. The high-efficiency scan heads and detectors, coupled with Nikon's unrivaled optics, provide superior confocal images. The system provides simultaneous acquisition of three fluorescent channels plus DIC in a single scan. Built on a reputation of incredible stability and operational simplicity, coupled with superior optical technologies, the C2+ confocal system is an essential laboratory tool.

ECLIPSE Ni-E Upright Microscope with Yokogawa CSU-X1 Confocal

The CSU-X1 field scanning confocal spinning disk system from Yokogawa Life Sciences, configured with Nikon’s ECLIPSE Ni-E upright microscope, allows users a flexible and powerful system for a wide range of imaging applications. Field scanners are renowned for their low dosage, specimen-friendly characteristics, making them ideal for live cell or organism applications.

ECLIPSE Ni-E Upright Microscope with High-speed Piezo Objective Positioning System

The fully motorized ECLIPSE Ni-E upright microscope, which enables automatic observation, responds to the needs of advanced research in which control of devices such as cameras and confocal systems is linked with microscope control, and supports a wide range of cutting-edge bioscience research.

SMZ25 Stereo Microscope

The Nikon SMZ25 stereo microscope is a high-end, versatile optical instrument designed for advanced research applications, featuring a revolutionary zoom system and a large zoom range. It provides exceptionally high-resolution images and a wide field of view, making it ideal for detailed, three-dimensional observations in fields like molecular biology, cell biology, neurobiology, embryology, developmental biology and systems biology.