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Center of Excellence

Center for Advanced Microscopy at UTHealth

The Center for Advanced Microscopy and Nikon Center of Excellence at UTHealth provides state of the art imaging capabilities as well as expertise to those within UTHealth and the Texas Medical Center who have a need for cutting edge imaging technology. The Center brings together scientists and Nikon’s technical expertise with the purpose of utilizing molecular, cellular, tissue, and whole animal imaging to understand normal and abnormal biological processes and how these translate into organismal physiologies and pathophysiologies.


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University of Texas Health Science Center
Department of Integrative Biology & Pharmacology
Medical School, Room MSB 4.532
6431 Fannin St.
Houston, TX 77030

Systems Available

N-SIM Structured Illumination Super Resolution System

  • Structured Illumination based super resolution imaging system
  • Provides up to 2-fold improvement in resolution in XY and Z
  • 2D, 3D, and TIRF modes available
  • Available wavelengths: 405, 445, 488, 514, 561, 647nm

A1Rsi HD Confocal and N-STORM Super Resolution System

  • High-Definition 1Kx1K resonant scanning confocal for high resolution, high speed imaging
  • High-sensitivity GaAsP spectral detector
  • Total Internal Reflection Fluorescence (TIRF) mode available
  • Stochastic Optical Reconstruction Microscopy (STORM) mode enables up to 10-fold improvement in resolution in XY and Z
  • Available wavelengths: 405, 445, 488, 514, 561, 647nm

A1R Confocal

  • High-speed resonant scanning confocal with simultaneous photo-stim and imaging capability
  • Environmental chamber for live-cell imaging
  • PFS autofocusing system
  • Available wavelengths: 405, 445, 488, 514, 561, 647nm
  • Widefield imaging capability

A1 Confocal and PicoQuant Fluorescence Lifetime Imaging

  • 4-line, high-resolution point scanning confocal (405, 488, 561, 640nm)
  • PicoQuant FLIM imaging system (439 and 483nm lasers)