Notes d’application

Development of Technology to Visualize Interaction of Osteoblasts and Osteoclasts in Living Bone Tissue

août 2021

A research group led by Professor Masaru Ishii (Immune cell biology), Graduate School of Medicine, Osaka University, has developed a technology to observe the inside of living bones, and to simultaneously visualize osteoblasts, which make new bone, and osteoclasts, which dissolve old bone, using the A1R MP+ multi-photon confocal microscope, which is capable of deep tissue imaging. This application note introduces an example of the world’s first successful imaging of the moment of direct contact and communication between osteoblasts and osteoclasts in living bone tissue.