Applications

2D Imaging

We provide imaging services for a variety of 2D model systems. These services include a broad portfolio of assays, live and fixed cell imaging on slide coverslips, dishes and multi-well plates, epifluorescence or confocal imaging modalities, and intelligent image acquisition and AI-supported analysis. Our broad portfolio of assays captures our strength, and are highly customizable to client-specific needs.

3D Imaging

We provide imaging services for a variety of 3D model systems. These services include a broad portfolio of assays, live and fixed cell imaging, time-lapse imaging, whole organism imaging, epifluorescence or confocal imaging modalities, intelligent image acquisition, and AI-supported analysis. Our broad portfolio of assays captures our strength, and are highly customizable to client-specific needs.

Spatial Biology

Advanced spatial biology technologies to perform high-plex spatial imaging and whole transcriptome spatial profiling. Assay functional markers, protein biomarkers, chemokines, cytokines and RNA within tissues, all while retaining spatial context.

Super-Resolution

Unlock the power of ultra-detailed cellular imaging with super-resolution technology. Achieve unmatched clarity, ultra-low noise, and heightened sensitivity—ideal for revealing fine biological structures that standard microscopy can’t resolve.

mRNA Quantification (smFISH) for Gene Expression Analysis

Single molecule fluorescence in situ hybridization (smFISH), known for its ability to quantify individual RNA molecules, is widely used to characterize spatio-temporal patterns of gene expression in single cells. At NBIL we harness this technique to provide RNA quantification services for research applications such as gene expression analysis in response to drug candidates, spatial biology studies, and more.

Whole Slide Scanning

We provide whole slide imaging services, brightfield or fluorescence, of fixed specimens for histology, pathology, gene expression, and spatial biology studies.

Pre-clinical Toxicology Services

Comprehensive imaging-based approaches for your toxicology studies during early drug development, drug safety assessments, and studies in MoA. Assess compound efficacy and efficiency in 2D and 3D cell culture models.

Histological Imaging and Analysis to Assess Disease Progression and Biomarker Expression

Customizable, automated, bias-free image acquisition and analysis for histology and pathology applications utilizing multiplexed chromogenic and fluorescent IHC, IF and ISH.

Automated Solutions for High-Content Imaging Applications

Generate consistent, high-quality data with Nikon’s turnkey automated microscopy and image analysis solutions.

Custom Image Processing and Analysis

Image processing has a wide variety of uses and is an integral part of most microscopy experiments, from clarifying low-signal images to preparing images for robust segmentation and quantification. Custom analysis workflows are used for applications from gathering single-cell statistics to training AI networks for detection of customer-defined features.