Entrevistas a investigadores

YOUR SWITCH TO THE FUTURE

Department of Biomedicine, University of Basel

Pascal Lorentz
Dr. Michael Abanto

Director of the Nikon Center of Excellence
Head of the Microscopy Core Facility

Research Outline: Immunology and infectious diseases, neurosciences, cancer biology, and tissue development and regeneration.

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Dr. Kevin Richetin

Our Nikon Microscopy Ambassador Dr. Kevin Richein is a neuroscience researcher studying Alzheimer’s disease and the development of tools for neurodegenerative diseases. In this interview video, Dr. Richetin discusses how they chose the Nikon microscope because its software NIS-Elements allows seamless integration of analysis and automation. He emphasizes that this unique capability is incredibly valuable for tracking particles with extremely high resolution over extended periods, a feature that sets Nikon apart.

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A step up in digital pathology using innovative digital microscopy.

Kitasato University Kitasato Institute Hospital
Director, Department of Pathology
Dr. Ichiro Maeda

Currently there are various treatment methods under development that could provide optimal medical care in response to the pathological attributes of each patient. Therefore, the role required of pathological diagnosis, which is indispensable for the planning of treatment policies and strategies, is becoming more important than ever before. However, the shortage of trained pathologists who assume this role is a common issue, not only in Japan, but also worldwide. To solve this problem, digital pathology has been attracting attention. In this article, we asked Dr. Ichiro Maeda, Director of the Department of Pathology, Kitasato University Kitasato Institute Hospital, for his impressions of using the digital image display optical microscope "ECLIPSE Ui".

*Dr. Maeda has provided feedback to Nikon on this microscope’s features and clinical usefulness based on his own personal experience.

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YOUR SWITCH TO THE FUTURE

Cincinnati Children’s Hospital Medical Center

Matthew Kofron, Ph.D.
Professor, UC Department of Pediatrics

Alicia Ostmann
Cincinnati Cystic Fibrosis Theratyping Research Center

Kentaro Iwasawa, M.D.
Takebe Lab, Division of Gastroenterology

Research Outline: Child health improvement. Organoid creation. Drug efficacy for cystic fibrosis patients.

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YOUR SWITCH TO THE FUTURE

European Institute for Molecular Imaging (EIMI)

Professor Friedmann Kiefer, Ph.D.

Department of Intravital Molecular Imaging

Research Outline: Elucidation of how molecular mechanisms shape human cells and tissues biologically. Multiscale imaging.

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YOUR SWITCH TO THE FUTURE

National Institutes of Natural Sciences, National Institute for Physiological Sciences

Tetsuhisa Otani, Ph.D. Assistant Professor

Division of Cell Structure

Research Outline: Epithelial tissue.

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YOUR SWITCH TO THE FUTURE

Korea Advanced Institute of Science and Technology

Professor Won Do Heo, Ph.D.

Department of Biological Sciences

Research Outline: Optogenetic and bio-imaging technologies.

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YOUR SWITCH TO THE FUTURE

Chinese Institute for Brain Research, Beijing, China

Dr. Hu Zhao, Principal Investigator

Research Outline: New tissue clearing methods, and building a neural connectome mapping platform based on these methods.

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“I believe this can change conventional imaging for pathologists”

Takeshi Sasaki
Professor, Project Leader, M.D. Ph.D
The University of Tokyo Hospital
Dept. of Next-Generation Pathology Information Networking

In medicine, pathologists play an extremely important role in confirming observation. They are often making observations with a microscope for long periods of time and the physical and mental burden of this is heavy. Aiming to reduce such stress issues for pathologists, Nikon has developed a new microscope for pathological examination, the ECLIPSE Ui, which allows pathologists to view high-resolution images of specimens on a monitor, rather than looking through eyepieces. Here, Dr. Takeshi Sasaki of the University of Tokyo Hospital, who has evaluated this microscope, talks about his impressions of it.

*Dr. Sasaki has provided feedback to Nikon on this microscope’s features and clinical usefulness based on his own personal experience.

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YOUR SWITCH TO THE FUTURE

Research Institute for Microbial Diseases (RIMD) at Osaka University

Hiroaki Miki, Professor
Yosuke Funato, Associate Professor
Osamu Hashizume, Assistant Professor

Division of Cellular and Molecular Biology, Department of Cellular Regulation

Research Outline: Analyzing the function of a membrane protein molecule called Cyclin M, which plays a role in ejecting magnesium ions from cells.

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Apoyando los estudios en el aula con el ECLIPSE Ei

“Es fácil enseñar a los estudiantes cómo usarlo, y ellos también lo encuentran fácil de usar”

La observación utilizando microscopios juega un papel extremadamente importante en el aprendizaje de los conceptos básicos de la ciencia. El ECLIPSE Ei de Nikon se desarrolló como un microscopio de uso educativo con el concepto de ser un ‘microscopio fácil de usar, incluso para los estudiantes que lo utilizan por primera vez’. Visitamos a la Sra. Rika Izumi, profesora de ciencias en Rikkyo Niiza Junior and Senior High School, Saitama, Japón, donde el ECLIPSE Ei está disponible en las aulas, para conocer los antecedentes y las razones para elegir este microscopio, la experiencia del usuario y las reacciones de los estudiantes.

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El ECLIPSE Ci-L plus contribuye a unos exámenes clínicos más cómodos.

“Además del alto rendimiento óptico, me di cuenta de que su diseño bien pensado ayuda en nuestro trabajo diario”.

Los exámenes clínicos juegan un papel importante en la atención médica. Nikon ha desarrollado un nuevo microscopio biológico, el ECLIPSE Ci-L plus, con el concepto de reducir el estrés físico y mental de los médicos y técnicos de laboratorio que utilizan microscopios a diario. En esta entrevista, hablamos con el Dr. Akira Yoshikawa del Departamento de Patología Anatómica del Centro Médico Kameda, un hospital insignia en la parte sur de la prefectura de Chiba, Japón, sobre su pensamiento después de emplear este microscopio y la lente de objetivo recientemente desarrollada para microscopía ‘CFI Plan Apochromat Lambda D’ para un uso práctico diario.

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Associate Prof. Dr. Klazina Kooiman and Dr. Ines Beekers

Associate Prof. Dr. Klazina Kooiman, Head of Therapeutic Ultrasound Contrast Agent Group, and Dr. Ines Beekers, Postdoctoral Researcher in the Department of Biomedical Engineering of the Thoraxcenter, Erasmus MC, Rotterdam, the Netherlands

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Dr. Yohei Yamauchi

Dr. Yohei Yamauchi, Principal Investigator, Cell biologist of viral infections, School of Cellular and Molecular Medicine, University of Bristol, UK

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Assistant Prof. Klazina Kooiman & Inés Beekers

Therapeutic Ultrasound Contrast Agent Group, Thoraxcenter, Department of Biomedical Engineering, Erasmus MC, Rotterdam

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Dr. Steven Nedellec and Dr. Tiphaine Douanne

Dr. Steven Nedellec, Facility Manager of MicroPICell, Université de Nantes, France and Dr. Tiphaine Douanne, Universite de Nantes, Signaling in Oncogenesis, Angiogenesis and Permeability, CRCINA INSERM U1232, France

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Dr. Tadahiro Iimura

Division of Bio-Imaging, Proteo-Science Center (PROS), Ehime University
Division of Analytical Bio-Medicine, Advanced Research Support Center (ADRES), Ehime University
Graduate School of Medicine, Ehime University

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Ronald D. Vale, Ph.D.

Professor and Vice-Chairman of the Department of Cellular and Molecular Pharmacology
Investigator, Howard Hughes Medical Institute (HHMI)
The University of California, San Francisco San Francisco, CA, USA

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Tamas Freund, Ph.D. and Istvan Katona, Ph.D.

Institute of Experimental Medicine of the Hungarian Academy of Sciences (IEM HAS)
Budapest, Hungary

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Maddy Parsons, Ph.D.

Group Leader (Royal Society University Research Fellow)
Randall Division of Cell and Molecular Biophysics
King’s College London
London, United Kingdom

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Paul Ronald Selvin, Ph.D.

Professor, Department of Physics, University of Illinois at Urbana-Champaign

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Bo Huang, Ph.D.

Assistant Professor, Department of Pharmaceutical Chemistry, Department of Biochemistry and Biophysics, University of California, San Francisco

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Atsushi Miyawaki, M.D., Ph.D.

Senior Team Leader, Laboratory for Cell Function Dynamics, RIKEN Brain Science Institute

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  • AZ-C1 macro confocal microscope system
  • 1x objective lens (AZ-Plan Apo, NA 0.1, W.D. 35 mm)
  • 2x objective lens (AZ-Plan Fluor, NA 0.2, W.D. 45 mm)

Prof. Staffan Strömblad, Ph.D.

Staffan Strömblad Ph.D. is group leader at the prestigious Karolinska Institutet, Stockholm, Sweden, an institution that awards the Physiology Nobel Prize yearly. He is also the head of the Live Cell Imaging Facility (LCI), in which the Nikon Center of Excellence for live cell imaging is integrate.

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Masato Nakagawa

So-called iPS cells are attracting considerable interest as pluripotent stem cells that may open up a whole new world of medicine. The Center for iPS Cell Research and Application (CiRA) at Kyoto University is pursuing a wide range of research activities that aim to realize regenerative medicine utilizing iPS cells. The Nikon BioStation CT cell culture observation system is being used in this iPS cell research and is contributing to its efficiency.

We were pleased to have had an opportunity to speak with Masato Nakagawa, who is engaged in iPS cell research at CiRA.

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Note: The institutions and job titles listed with each researcher reflect their affiliation at the time of the interview.