Center of Excellence
The Scripps Research Institute
Researchers at The Scripps Research Institute (TSRI) can now probe more deeply and clearly into the microscopic elements of cells with the recent opening of a new Nikon Center of Excellence on the California campus, featuring the latest in advanced imaging technology.
Contact
CofE Director
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Address
The Scripps Research InstituteDept. of Molecular and Cellular Neuroscience
10550 N. Torrey Pines Road
DNC 210
La Jolla, CA 92037
Systems Available
N-STORM/TIRF/A1Rsi Super-Resolution & Confocal System
Featuring both the N-STORM single molecule localization and A1R HD resonant scanning confocal, this system is ready for applications ranging from super-resolution to fast live-cell confocal or TIRF.
Components
- Ti-E inverted microscope with Perfect Focus System (PFS)
- A1-DUS 32-channel spectral detector
N-STORM super-resolution single molecule localization microscopy system
- LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
- Mad City Labs Nano-Z series Z-axis piezo stage
- DU4 4-channel confocal detector
- Andor iXon 897 EMCCD camera
NIS-Elements software
A1Rsi Resonant Scanning Confocal System
Using the Nikon A1Rsi resonant scanning confocal system with spectral detector, this system is made for linear unmixing of multiply labeled samples.
Components
- Ti-E inverted microscope with Perfect Focus System (PFS)
- A1Rsi resonant scanning confocal system
LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
- A1-DUS 32-channel spectral detector
- DU4G GaAsP 4-channel confocal detector
NIS-Elements software
C2 Point Scanning Confocal System
This C2 point-scanning confocal system is configured on a 90i upright microscope and a great option for applications requiring optical sectioning.
Components
- Eclipse 90i upright microscope
C2 point scanning confocal system
- LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
- DU3 3-channel confocal detector
NIS-Elements software
A1R Resonant Scanning Confocal System
This A1R resonant scanning confocal system is configured on an FN1 upright microscope, and providing added flexiiblity for larger samples.
Components
FN1 upright microscope
A1R resonant scanning confocal system
LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
- DU4G GaAsP 4-channel confocal detector
NIS-Elements software
N-STORM/TIRF Super-Resolution System
While this microscope features the N-STORM localization microscopy system for super-resolution, it can also be operated as a fast live-cell TIRF microscope.
Components
- Ti-E inverted microscope with Perfect Focus System (PFS)
N-STORM super-resolution single molecule localization microscopy system
- LUN-V 4-line laser unit (405nm, 488nm, 561nm, 647nm)
- Mad City Labs Nano-Z series Z-axis piezo stage
- Hamamatsu ORCA-Flash4.0 V2+ sCMOS camera
- World Precision Instruments AirTherm stage heater
- In Vivo Scientific CO2 controller
NIS-Elements software
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