Centro de Excelência

The Scripps Research Institute

Researchers at The Scripps Research Institute (TSRI) can now probe more deeply and clearly into the microscopic elements of cells with the recent opening of a new Nikon Center of Excellence on the California campus, featuring the latest in advanced imaging technology.

Contato

CofE Director

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Address

The Scripps Research Institute
Dept. of Molecular and Cellular Neuroscience
10550 N. Torrey Pines Road
DNC 210
La Jolla, CA 92037

Systems Available

N-STORM/TIRF/A1Rsi Super-Resolution & Confocal System

Featuring both the N-STORM single molecule localization and A1R HD resonant scanning confocal, this system is ready for applications ranging from super-resolution to fast live-cell confocal or TIRF.

Components

Ti-E inverted microscope with Perfect Focus System (PFS)
A1-DUS 32-channel spectral detector
N-STORM super-resolution single molecule localization microscopy system
LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
Platina piezo de eixo Z da série Nano-Z, da Mad City Labs
DU4 4-channel confocal detector
Andor iXon 897 EMCCD camera
NIS-Elements software

A1Rsi Resonant Scanning Confocal System

Using the Nikon A1Rsi resonant scanning confocal system with spectral detector, this system is made for linear unmixing of multiply labeled samples.

Components

Ti-E inverted microscope with Perfect Focus System (PFS)
A1Rsi resonant scanning confocal system
LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
A1-DUS 32-channel spectral detector
DU4G GaAsP 4-channel confocal detector
NIS-Elements software

C2 Point Scanning Confocal System

This C2 point-scanning confocal system is configured on a 90i upright microscope and a great option for applications requiring optical sectioning.

Components

C2 point scanning confocal system
LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
DU3 3-channel confocal detector
NIS-Elements software

This A1R resonant scanning confocal system is configured on an FN1 upright microscope, and providing added flexiiblity for larger samples.

Components

FN1 upright microscope
LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
DU4G GaAsP 4-channel confocal detector
NIS-Elements software

Sistema de super-resolução N-STORM/TIRF

While this microscope features the N-STORM localization microscopy system for super-resolution, it can also be operated as a fast live-cell TIRF microscope.

Components

Ti-E inverted microscope with Perfect Focus System (PFS)
N-STORM super-resolution single molecule localization microscopy system
Unidade de laser de 4 linhas LUN-V (405 nm, 488 nm, 561 nm, 647nm)
Platina piezo de eixo Z da série Nano-Z, da Mad City Labs
Hamamatsu ORCA-Flash4.0 V2+ sCMOS camera
World Precision Instruments AirTherm stage heater
In Vivo Scientific CO2 controller
NIS-Elements software