Time-lapse imaging analysis of angiogenesis induction using a 3D model
It is known that a decrease in the homeostasis function of blood vessels is involved in the onset and progression of various diseases and pathological conditions such as cancer, arteriosclerosis, chronic inflammation, and ischemia. Against this background, it is very important to understand the detailed mechanisms relating to new vascular structure formation by angiogenesis etc. and microvessel damage. This application note introduces an example of detailed observation and analysis of a 3D angiogenesis structure (in vitro perfusion angiogenesis model) with an AX/ AX R confocal microscope, using the Mimetas’ OrganoPlate® 3D tissue culture platform.