Digital pathology based on intrinsic fluorescence spectra of liver fibrosis using a multiphoton microscope
In recent years, an increase in metabolic syndrome caused by the accumulation of visceral fat has become a widespread problem. Nonalcoholic fatty liver disease (NAFLD) and its severe form, nonalcoholic steatohepatitis (NASH), are metabolic syndromes in the liver that progress to liver cirrhosis and hepatocellular carcinoma. The development of accurate and early diagnostic techniques for pathological conditions with respect to NAFLD/NASH is one society’s most significant issues.
This application note introduces a quantitative evaluation technique for liver fibrosis developed by Dr. Takashi Saitou and Dr. Takeshi Imamura of the Department of Molecular Pathogenesis, and Dr. Yoichi Hiasa of the Department of Gastroenterology and Metabology, Graduate School of Medicine, Ehime University.