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The Scripps Research Institute

Researchers at The Scripps Research Institute (TSRI) can now probe more deeply and clearly into the microscopic elements of cells with the recent opening of a new Nikon Center of Excellence on the California campus, featuring the latest in advanced imaging technology.

联系方式

CofE Director

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Address

The Scripps Research Institute
Dept. of Molecular and Cellular Neuroscience
10550 N. Torrey Pines Road
DNC 210
La Jolla, CA 92037


Systems Available

N-STORM/TIRF/A1Rsi Super-Resolution & Confocal System

Featuring both the N-STORM single molecule localization and A1R HD resonant scanning confocal, this system is ready for applications ranging from super-resolution to fast live-cell confocal or TIRF.

Components

  • Ti-E inverted microscope with Perfect Focus System (PFS)
  • A1-DUS 32-channel spectral detector
  • N-STORM super-resolution single molecule localization microscopy system
  • LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
  • Mad City Labs Nano-Z series Z-axis piezo stage
  • DU4 4-channel confocal detector
  • Andor iXon 897 EMCCD camera
  • NIS-Elements software

A1Rsi Resonant Scanning Confocal System

Using the Nikon A1Rsi resonant scanning confocal system with spectral detector, this system is made for linear unmixing of multiply labeled samples.

Components

  • Ti-E inverted microscope with Perfect Focus System (PFS)
  • A1Rsi resonant scanning confocal system
  • LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
  • A1-DUS 32-channel spectral detector
  • DU4G GaAsP 4-channel confocal detector
  • NIS-Elements software

C2 Point Scanning Confocal System

This C2 point-scanning confocal system is configured on a 90i upright microscope and a great option for applications requiring optical sectioning.

Components

  • Eclipse 90i upright microscope
  • C2 point scanning confocal system
  • LU4A 4-line laser unit (405nm, 488nm, 561nm, 638nm)
  • DU3 3-channel confocal detector
  • NIS-Elements software

A1R Resonant Scanning Confocal System

This A1R resonant scanning confocal system is configured on an FN1 upright microscope, and providing added flexiiblity for larger samples.

Components

  • FN1 upright microscope
  • A1R resonant scanning confocal system
  • LUN-4 4-line laser unit (405nm, 488nm, 561nm, 640nm)
  • DU4G GaAsP 4-channel confocal detector
  • NIS-Elements software

N-STORM/TIRF Super-Resolution System

While this microscope features the N-STORM localization microscopy system for super-resolution, it can also be operated as a fast live-cell TIRF microscope.

Components

  • Ti-E inverted microscope with Perfect Focus System (PFS)
  • N-STORM super-resolution single molecule localization microscopy system
  • LUN-V 4-line laser unit (405nm, 488nm, 561nm, 647nm)
  • Mad City Labs Nano-Z series Z-axis piezo stage
  • Hamamatsu ORCA-Flash4.0 V2+ sCMOS camera
  • World Precision Instruments AirTherm stage heater
  • In Vivo Scientific CO2 controller
  • NIS-Elements software