卓越中心 for Translational Research

University of Basel - Department of Biomedicine (DBM)

The DBM Center of Excellence for Translational Research is the result of a long-lasting partnership between Nikon and the Department of Biomedicine (DBM). The two directors, Mike Abanto and Pascal Lorentz, developed the unit from scratch into an excellent microscopy core facility within the last 15 years. Together with their team of experts, they support researchers in the fields of oncology, immunology, neurobiology, stem cells, and regenerative medicine.

The Department of Biomedicine (DBM) is part of the medical faculty of the University of Basel and unites biomedical research. The DBM is a joint venture of the University of Basel, the University Hospital Basel, and the University Children’s Hospital beider Basel. At the DBM, clinicians and researchers work side-by-side creating excellent bench-to-bedside research opportunities that contribute to its translational reputation internationally.

The DBM Nikon Center of Excellence not only offers a variety of cutting-edge microscopes and has excellent staff, but they are also leaders in automation using Nikon’s programming interface, called JOBS.

With their equipment, which ranges from 2-Photon, super-resolution, confocal to wide-field microscopy, and their skills, the facility provides optimal conditions to foster competitive research.

联系方式

email hidden; JavaScript is required

email hidden; JavaScript is required

网站

University of Basel - Department of Biomedicine (DBM)

可用系统

AX R with NSPARC Confocal

Components

Crest X-Light V3 Confocal System

Components

  • ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
  • Piezo stage
  • LIS incubation chamber (gas & temperature controlled)
  • CoolLED pE-300
  • Lumencor Celestra (405 nm, 446 nm, 477 nm, 520 nm, 546 nm, 638 nm, 749 nm)
  • Crest X-Light V3 L-FOV spinning disk confocal system
  • Photometrics Prime95B sCMOS camera
  • Photometrics Kinetix sCMOS camera
  • NIS-Elements Advanced Research with JOBS

Crest X-Light V3 DeepSIM System

Components

  • ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
  • Piezo stage
  • CoolLED pE-300
  • OkoLab stage top incubation system 
  • Lumencor Celestra (405 nm, 445 nm, 477 nm, 510 nm, 546 nm, 640 nm, 749 nm)
  • Crest X-Light V3 DeepSIM L-FOV spinning disk confocal system
  • Photometrics Prime95B sCMOS camera
  • Photometrics Kinetix sCMOS camera
  • NIS-Elements Advanced Research with JOBS

Crest Cicero Confocal System

Components

  • ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)
  • Motorized stage with encoders
  • LIS incubation chamber (temperature controlled)
  • OkoLab stage top incubation system
  • D-LEDI fluorescence LED
  • Lumencor Celestra (405 nm, 446 nm, 477 nm, 520 nm, 546 nm, 638 nm, 749 nm)
  • Crest Cicero spinning disk confocal system
  • Photometrics Kinetix sCMOS camera
  • NIS-Elements Advanced Research with JOBS

CSU-W1 Spinning Disk Confocal System

Components

  • ECLIPSE Ti-E inverted microscope with Perfect Focus System (PFS)
  • Ludl motorized scanning stage with z-piezo
  • LIS incubation chamber (temperature controlled)
  • OkoLab stage top incubation system
  • CoolLed pE-300-W
  • Yokogawa CSU-W1 spinning disk confocal
  • ILas-2 TIRF dual laser illuminator for TIRF microscopy
  • 2D-VisiFRAP realtime scanner
  • Hamamatsu ORCA-Flash4.0 V2 sCMOS camera
  • Hamamatsu EM CCD 2014 camera
  • VisiView Premier

CSU-W1 Spinning Disk Confocal System

Components

  • ECLIPSE Ti-E inverted microscope with Perfect Focus System (PFS)
  • Prior motorized scanning stage
  • OkoLab enclosure incubation system
  • Prior plate-loading robot
  • CoolLED pE-300
  • Yokogawa CSU-W1 spinning disk confocal
  • Photometrics Prime95B sCMOS camera
  • Hamamatsu ImagEM EMCCD camera
  • NIS-Elements Advanced Research with JOBS

A1 2-Photon Confocal System

Components

  • ECLIPSE Ti2-E inverted microscope with Perfect Focus System (PFS)
  • LIS incubation chamber (temperature controlled)
  • Additional motorized stage (Luis/Neumann) for periscope applications
  • 2-photon class IV laser
  • A1 confocal and spectral detector
  • NIS-Elements Advanced Research with JOBS

ECLIPSE Ti-E Inverted Microscope

Components

ECLIPSE Ti2 Inverted Microscope (left-handed)

Components

ECLIPSE Ti2 Inverted Microscope (right-handed)

Components

ECLIPSE Ti2 2.3.PO Inverted Microscope

Components

ECLIPSE E600 Upright Microscope

Components

  • ECLIPSE E600
  • Nikon DXM-1200F digital camera
  • Nikon ACT-1 software

ECLIPSE Ts2 Inverted Microscope

Components

SMZ25 Stereo Microscope

Components

ECLIPSE Ti2-E CSU-W1 with SoRa Confocal System

Components

  • ECLIPSE Ti2-E inverted microscope with Perfect Focus System 4 (PFS4)

  • Okolab stage top incubator for hypoxia and normoxia

  • D-LEDI fluorescence LED

  • Lumencor Ziva light source (405 nm, 445 nm, 486 nm, 549 nm, 639 nm, 683 nm, 751 nm)

  • With 50µm and SoRa spinning disks

  • Polarised light and DIC capabilities for BSL2 experiments (no piezo)

  • Hamamatsu ORCA-FusionBT

  • Andor iXon Life

  • NIS-Elements Advanced Research with JOBS

ECLIPSE Ti2-E (for BSL2 experiments)

Components

  • LIS incubation box for temperature control
  • Kinetix cam
  • pE-800 light source
  • (no piezo)